Discover practical ways to critically appraise scientific literature, including the conduction and interpretation of systematic reviews and meta-analyses. Additionally, you will learn how to conduct literature searches using online academic databases, hear about economic evaluations, and understand how clinical practice guidelines are used to guide decision making.  This course includes the following 11 lectures: Overview of Systematic ReviewsFinding and Managing the Evidence from the Biomedical LiteratureIntervention Reviews MethodologyMeta-Analysis of Clinical Trials: Direct ComparisonsIntroduction to Meta-Analysis: Indirect ComparisonsMeta-Analysis of Non-Randomized StudiesDiagnostic Test EvaluationMeta-SynthesisClinical Practice GuidelinesEconomic EvaluationDecision Analysis for Outcomes ResearchThis course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods. This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

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